Prasugrel

Prasugrel
Prasugrel

Uses

Prasugrel is used along with aspirin to prevent serious or life-threatening problems with the heart and blood vessels in people who have had a heart attack or severe chest pain and have been treated with angioplasty (procedure to open the blood vessels that supply blood to the heart). Prasugrel is in a class of medications called anti-platelet medications. It works by preventing platelets (a type of blood cell) from collecting and forming clots that may cause a heart attack or stroke.

Side Effects Of Prasugrel

Prasugrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

Some side effects can be serious. If you experience any of these symptoms or those listed in the WARNING section, call your doctor immediately:

  • fever
  • weakness
  • paleness
  • purple patches on the skin
  • yellowing of the skin or eyes
  • shortness of breath
  • slow, fast, or irregular heartbeat
  • headache
  • confusion
  • seizures
  • slow or difficult speech
  • sudden weakness of an arm or leg
  • stomach pain
  • nausea
  • vomiting
  • diarrhea
  • decreased urination
  • rash
  • swelling of the eyes, face, mouth, lips, tongue, throat, arms, hands, feet, ankles, or lower legs

Prasugrel may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Warnings & Precautions

Before taking prasugrel:

  • tell your doctor and pharmacist if you are allergic to prasugrel, clopidogrel (Plavix), ticlopidine (Ticlid), any other medications, or any of the ingredients in prasugrel tablets. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the WARNING section and any of the following: opioids such as codeine, fentanyl (Duragesic, Subsys), hydrocodone (Hysingla, Zohydro ER, in Vicodin), morphine (Astramorph, Kadian), or oxycodone (in Percocet, in Roxicet, others). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had kidney disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking prasugrel, call your doctor.
  • talk to your doctor about the risks and benefits of taking prasugrel if you are 75 years of age or older.

Prasugrel Dosage

Prasugrel comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take prasugrel at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take prasugrel exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the tablet whole; do not split, break, chew, or crush it.

Prasugrel will help prevent serious problems with your heart and blood vessels only as long as you take the medication. Do not stop taking prasugrel without talking to your doctor. If you stop taking prasugrel, there is a higher risk that you may have a heart attack, develop a blood clot, or die.

Other

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Source

All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.