Delafloxacin

Uses

Delafloxacin is used to treat skin infections and certain types of pneumonia (an infection of the lungs) caused by bacteria in adults. Delafloxacin is in a class of antibiotics called fluoroquinolones. It works by killing the bacteria that cause infections.

Antibiotics such as delafloxacin will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Side Effects Of Delafloxacin

Delafloxacin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea
  • vomiting
  • diarrhea
  • headache

Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, stop taking delafloxacin and call your doctor immediately or get emergency medical treatment:

  • severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)
  • rash, itching, hives, shortness of breath, tingling or swelling of the face or throat, or fainting
  • extreme thirst or hunger; pale skin; feeling shaky or trembling; fast or fluttering heartbeat; sweating; frequent urination; trembling; blurred vision; or unusual anxiety
  • sudden pain in the chest, stomach, or back

Delafloxacin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Warnings & Precautions

Before taking delafloxacin:

  • tell your doctor and pharmacist if you are allergic or have had a severe reaction to delafloxacin, any other quinolone or fluoroquinolone antibiotic such as ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), and ofloxacin, any other medications, or any of the ingredients in delafloxacin tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and insulin or other medications to treat diabetes such as chlorpropamide, glimepiride (Amaryl, in Duetact), glipizide (Glucotrol), glyburide (DiaBeta), tolazamide, and tolbutamide. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • if you are taking antacids containing aluminum hydroxide or magnesium hydroxide (Maalox, Mylanta, others), or certain medications such as didanosine (Videx) solution, sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc, take these medications 6 hours before or 2 hours after you take delafloxacin.
  • tell your doctor if you have or have ever had an aortic aneurysm (swelling of the large artery that carries blood from the heart to the body), high blood pressure, peripheral vascular disease (poor circulation in the blood vessels), Marfan syndrome (a genetic condition that can affect the heart, eyes, blood vessels and bones), Ehlers-Danlos syndrome (a genetic condition that can affect the skin, joints, or blood vessels), diabetes, or problems with low blood sugar.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking delafloxacin, call your doctor.

Delafloxacin Dosage

Delafloxacin comes as a tablet to take by mouth. It is usually taken with or without food twice a day (every 12 hours). Take delafloxacin at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take delafloxacin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

You should begin to feel better during the first few days of treatment with delafloxacin. If your symptoms do not improve or get worse, call your doctor.

Take delafloxacin until you finish the prescription, even if you feel better. Do not stop taking delafloxacin without talking to your doctor unless you experience certain serious side effects listed in the WARNING or SIDE EFFECTS sections. If you stop taking delafloxacin too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Other

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body’s response to delafloxacin. If you have diabetes, your doctor may ask you to check your blood sugar more often while taking delafloxacin.

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the delafloxacin, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Source

All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.