Uses of Flutamide
Flutamide is used together with a luteinizing hormone-releasing hormone agonist (LHRH; a type of hormonal injection such as leuprolide [Lupron, Eligard], goserelin [Zoladex], or triptorelin [Trelstar]) to treat certain types of prostate cancer. Flutamide is in a class of medications called nonsteroidal antiandrogens. It works by blocking the effects of androgen (a male hormone) to stop the growth and spread of cancer cells.
Side Effects Of Flutamide
Flutamide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- diarrhea
- nausea
- vomiting
- loss of appetite
- hot flashes
- the decrease in sexual ability or desire
- breast enlargement in men
- drowsiness
- confusion
- depression
- anxiety
- swelling of the hands, feet, ankles, or lower legs
- blue-green or orange-colored urine
Some side effects can be serious. If you experience any of the symptoms listed in the WARNINGS section, call your doctor immediately.
Although it is rare, some men taking flutamide have developed breast cancer. Talk to your doctor about the risks of taking this medication.
It may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
Warnings & Precautions
Before taking flutamide:
- tell your doctor and pharmacist if you are allergic to flutamide or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention anticoagulants (”blood thinners”) such as warfarin (Coumadin).
- tell your doctor if you smoke and if you have or have ever had any inherited blood diseases such as glucose-6-phosphate dehydrogenase (G-6-PD) deficiency or hemoglobin M disease.
- you should know that flutamide is only for use in men. If taken by pregnant women, flutamide can harm the fetus. Women who are or may become pregnant should not take flutamide. If you take flutamide while you are pregnant, call your doctor.
- ask your doctor about the safe use of alcoholic beverages while you are taking flutamide. Flutamide may cause facial flushing, and drinking alcohol can make it worse.
Flutamide Dosage
Flutamide comes as a capsule to take by mouth. It is usually taken with or without food every 8 hours (three times a day.) Take flutamide at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take flutamide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Continue to take flutamide along with the LHRH agonist treatment even if you feel well. Do not stop taking either medication without talking to your doctor.
Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.
Other
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body’s response to flutamide.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Source
All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.
