Rotavirus Vaccine

Uses

Rotavirus is a virus that causes diarrhea, mostly in babies and young children. The diarrhea can be severe, and lead to dehydration. Vomiting and fever are also common in babies with rotavirus. Before the rotavirus vaccine, rotavirus disease was a common and serious health problem for children in the United States. Almost all children in the U.S. had at least one rotavirus infection before their 5th birthday.

Every year before the vaccine was available:

  • more than 400,000 young children had to see a doctor for illness caused by rotavirus,
  • more than 200,000 had to go to the emergency room,
  • 55,000 to 70,000 had to be hospitalized, and
  • 20 to 60 died.

Since the introduction of the vaccine, hospitalizations and emergency visits for rotavirus have dropped dramatically.

Side Effects Of Rotavirus Vaccine

With a vaccine, like any medicine, there is a chance of side effects. These are usually mild and go away on their own. Serious side effects are also possible but are rare.

Most babies who get the vaccine do not have any problems with it. But some problems have been associated with the rotavirus vaccine:

Mild problems following rotavirus vaccine:

  • Babies might become irritable, or have mild, temporary diarrhea or vomiting after getting a dose of rotavirus vaccine.
  • Severe problems following rotavirus vaccine:
  • Intussusception is a type of bowel blockage that is treated in a hospital and could require surgery. It happens “naturally” in some babies every year in the United States, and usually, there is no known reason for it.
  • There is also a small risk of intussusception from rotavirus vaccination, usually within a week after the 1st or 2nd vaccine dose. This additional risk is estimated to range from about 1 in 20,000 to 1 in 100,000 U.S. infants who get rotavirus vaccine. Your doctor can give you more information.
  • Problems that could happen after any vaccine:
  • Any medication can cause a severe allergic reaction. Such reactions from a vaccine are very rare, estimated at fewer than 1 in a million doses, and usually happen within a few minutes to a few hours after the vaccination.

As with any medicine, there is a very remote chance of a vaccine causing a serious injury or death.

Warnings & Precautions

A baby who has had a (life-threatening allergic reaction to a dose of rotavirus vaccine should not get another dose. A baby who has a severe allergy to any part of the rotavirus vaccine should not get the vaccine. Tell your doctor if your baby has any severe allergies that you know of, including a severe allergy to latex.

Babies with “severe combined immunodeficiency” (SCID) should not get rotavirus vaccine.

Babies who have had a type of bowel blockage called “intussusception” should not get rotavirus vaccine.

Babies who are mildly ill can get the vaccine. Babies who are moderately or severely ill should wait until they recover. This includes babies with moderate or severe diarrhea or vomiting.

Check with your doctor if your baby’s immune system is weakened because of the following:

  • HIV/AIDS, or any other disease that affects the immune system
  • treatment with drugs such as steroids
  • cancer, or cancer treatment with x-rays or drugs

Rotavirus Vaccine Dosage

Two brands of rotavirus vaccine are available. Your baby will get either 2 or 3 doses, depending on which vaccine is used.

Doses are recommended at these ages:

  • First Dose: 2 months of age
  • Second Dose: 4 months of age
  • Third Dose: 6 months of age (if needed)

Your child must get the first dose before 15 weeks of age, and the last by age 8 months. Rotavirus vaccine may safely be given at the same time as other vaccines.

Almost all babies who get the rotavirus vaccine will be protected from severe rotavirus diarrhea. And most of these babies will not get rotavirus diarrhea at all.

The vaccine will not prevent diarrhea or vomiting caused by other germs.

Another virus called porcine circovirus (or parts of it) can be found in both rotavirus vaccines. This is not a virus that infects people, and there is no known safety risk.

Other

Ask your doctor. He or she can give you the vaccine package insert or suggest other sources of information.

Call your local or state health department.

Source

All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.