Crisaborole Topical


Crisaborole topical is used to treat eczema (atopic dermatitis; a skin condition which causes the skin to be dry and itchy and to sometimes develop red, scaly rashes) in adults and children 3 years of age and older. Crisaborole is in a class of medications called phosphodiesterase inhibitors. It works by blocking the action of certain natural substances in the body that cause inflammation.

Side Effects Of Crisaborole Topical

Crisaborole topical may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • burning or stinging on the area of skin where the ointment was applied

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • hives
  • skin redness, itching, or swelling where crisaborole was applied or anywhere on the body

Crisaborole may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

Warnings & Precautions

Before using topical crisaborole:

  • tell your doctor and pharmacist if you are allergic to crisaborole, any other medications, or any of the ingredients in crisaborole ointment. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal or topical products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using crisaborole, call your doctor.

Dosage Of Crisaborole Topical

  • Crisaborole comes as an ointment to apply to the skin. It is usually applied twice a day. Use crisaborole at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use crisaborole topical exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
  • The ointment is only for use on the skin. Be careful not to get crisaborole ointment in your eyes, mouth, or vagina.
  • To use the ointment, follow these steps:
  • Wash your hands with soap and water.
  • Be sure that the skin in the affected area is dry.
  • Apply a thin layer of crisaborole topical ointment to all affected areas of your skin. Rub the ointment into your skin gently and completely.
  • Wash your hands with soap and water to remove any leftover crisaborole ointment. Do not wash your hands if you are treating them with crisaborole topical ointment. If a caregiver has applied the ointment, they should wash their hands after applying the ointment.
  • Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.


Keep all appointments with your doctor.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.


All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.