Ertapenem Injection

Uses

Ertapenem injection is used to treat certain serious infections, including pneumonia and urinary tract, skin, diabetic foot, gynecological, pelvic, and abdominal (stomach area) infections, that are caused by bacteria. It is also used for the prevention of infections following colorectal surgery. Ertapenem is in a class of medications called carbapenem antibiotics. It works by killing bacteria.

Antibiotics such as ertapenem injection will not work for colds, flu, or other viral infections. Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Side Effects Of Ertapenem Injection

Ertapenem injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea
  • vomiting
  • diarrhea
  • constipation
  • headache
  • dizziness
  • stomach pain
  • fever
  • cough
  • confusion
  • difficulty falling asleep or staying asleep
  • redness or irritation at the injection site
  • swelling, redness, burning, itching, or irritation of the vagina
  • swelling of the hands, feet, ankles, or lower legs

Some side effects can be serious. If you experience any of these symptoms, stop using ertapenem injection and call your doctor immediately or get emergency medical treatment:

  • severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)
  • hives
  • rash
  • itching
  • difficulty breathing or swallowing
  • seizures
  • unusual tiredness or weakness
  • pale skin
  • fast or irregular heartbeat
  • shortness of breath
  • chest pain

Ertapenem injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Warnings & Precautions

Before taking ertapenem injection:

  • tell your doctor and pharmacist if you are allergic to ertapenem; other carbapenem antibiotics such as imipenem/cilastatin (Primaxin), doripenem (Doribax), or meropenem (Merrem); local anesthetics such as bupivacaine (Marcaine), etidocaine (Duranest), lidocaine, mepivacaine (Carbocaine, Prolocaine), or prilocaine (Citanest); cephalosporins such as cefaclor (Ceclor), cefadroxil (Duricef), or cephalexin (Keflex), other beta-lactam antibiotics such as penicillin or amoxicillin (Amoxil, Trimox, Wymox), any other medications, or any of the ingredients in ertapenem injection. Ask your pharmacist or check the manufacturer’s patient information for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: probenecid (Probalan) or valproic acid (Depakene, Depakote). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever brain lesions, seizures, or kidney disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using ertapenem injection, call your doctor.

Dosage Of Ertapenem Injection

Ertapenem injection comes as a powder to be mixed with liquid to be injected intravenously (into a vein) or intramuscularly (into a muscle). It is infused (injected slowly) intravenously over a period of at least 30 minutes once or twice a day for up to 14 days. It is also may be given once or twice a day intramuscularly for up to 7 days. The length of treatment depends on the type of infection being treated. Your doctor will tell you how long to use ertapenem injection. After your condition improves, your doctor may switch you to another antibiotic that you can take by mouth to complete your treatment.

You may receive ertapenem injection in a hospital, or you may use the medication at home. If you will be using ertapenem injection at home, use it at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or other healthcare provider to explain any part you do not understand. Use ertapenem injection exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

If you will be using ertapenem injection at home, your health care provider will show you how to use the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions. Ask your healthcare provider what to do if you have any problems infusing ertapenem injection.

You should begin to feel better during the first few days of treatment with ertapenem injection. If your symptoms do not improve or if they get worse, call your doctor.

Use ertapenem injection until you finish the prescription, even if you feel better. If you stop using ertapenem injection too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.

Other

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body’s response to ertapenem injection.

Do not let anyone else use your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish using ertapenem injection, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Source

All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.