Plazomicin Injection


Plazomicin injection is used to treat serious urinary tract infections, including kidney infections, that are caused by bacteria. Plazomicin injection is in a class of medications called aminoglycoside antibiotics. It works by killing bacteria.

Antibiotics such as plazomicin injection will not work for colds, flu, or other viral infections. Taking or using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Side Effects Of Plazomicin Injection

Plazomicin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • diarrhea

Some side effects can be serious. If you experience any of these symptoms or those listed in the WARNINGS and PRECAUTIONS section, call your doctor immediately or get emergency medical treatment:

  • rash
  • itching
  • hives
  • swelling of the eyes, face, throat, tongue, or lips
  • difficulty breathing or swallowing
  • severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)

Plazomicin may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

Warnings & Precautions

Before using plazomicin injection:

  • tell your doctor and pharmacist if you are allergic to plazomicin injection; other aminoglycoside antibiotics such as amikacin, gentamicin, neomycin, streptomycin, or tobramycin; any other medications; or any of the ingredients in plazomicin injection. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the WARNINGS and PRECAUTIONS section. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while using plazomicin injection, call your doctor immediately. Plazomicin may harm the fetus.
  • tell your doctor if you are breastfeeding.

Dosage Of Plazomicin Injection

Plazomicin injection comes as a liquid to be injected intravenously (into a vein). When plazomicin is injected intravenously, it is usually infused (injected slowly) over a period of 30 minutes once daily. The length of your treatment is usually 4 to 7 days.

You may receive plazomicin injection in a hospital or you may administer the medication at home. If you will be receiving plazomicin injection at home, your healthcare provider will show you how to use the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions.

You should begin to feel better during the first few days of treatment with plazomicin injection. If your symptoms do not improve or get worse, tell your doctor.

Use plazomicin injection until you finish the prescription, even if you feel better. If you stop using plazomicin injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.


It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.


All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.