Uses
Tagraxofusp-erzs injection is used to treat blastic plasmacytoid dendritic cell neoplasm (BPDCN; a blood cancer that causes skin lesions and may spread to the bone marrow and lymphatic system) in adults and children 2 years of age and older. Tagraxofusp-erzs is in a class of medications called CD123 cytotoxin. It works by killing cancer cells.
Side Effects Of Tagraxofusp-erzs Injection
Tagraxofusp-erzs may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- nausea
- vomiting
- constipation
- diarrhea
- extreme tiredness
- headache
- decreased appetite
- sore throat
- pain in the back, arms, or legs
- cough
- difficulty falling asleep or staying asleep
- feeling nervous or confused
- nose bleed
- small red, brown, or purple spots on the skin
Some side effects of tagraxofusp-erzs injection can be serious. If you experience any of these symptoms or those listed in the WARNING section call your doctor immediately or get emergency medical treatment:
- rash, itching, difficulty breathing, mouth sores, or swelling
- extreme tiredness, yellowing of skin or eyes, loss of appetite, pain in the upper right part of the stomach
- fever, chills
- fast heartbeat
- blood in urine
Tagraxofusp-erzs may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
Warnings & Precautions
Before receiving tagraxofusp-erzs:
- tell your doctor and pharmacist if you are allergic to tagraxofusp-erzs, any other medications, or any of the ingredients in tagraxofusp-erzs injection. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you are pregnant, or plan to become pregnant. You must take a pregnancy test within 7 days before starting treatment. You should not become pregnant during your treatment with tagraxofusp-erzs injection. Use effective birth control during treatment and for 7 days after your final dose. If you become pregnant while receiving tagraxofusp-erzs, call your doctor.
- tell your doctor if you are breastfeeding. You should not breastfeed during your treatment with tagraxofusp-erzs and for 7 days after your final dose.
Dosage Of Tagraxofusp-erzs Injection
Tagraxofusp-erzs injection comes as a solution (liquid) to be diluted and injected intravenously (into a vein) over 15 minutes. It is usually given once a day on days 1, 2, 3, 4 and 5 of a 21 day treatment cycle. For the first treatment cycle, you will need to stay in the hospital until 24 hours after your last (5th) dose so that the doctors and nurses can watch you carefully for any side effects. For the following treatment cycles, you will probably only need to stay in the hospital for 4 hours after each dose.
Your doctor will probably treat you with other medications about one hour before each dose to help prevent certain side effects. Be sure to tell the doctor how you are feeling during your treatment with tagraxofusp-erzs injection. Your doctor may need to delay or stop your treatment if you experience certain side effects.
Other
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Source
All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.
