Uses
Rimegepant is used to treat the symptoms of migraine headaches (severe, throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound or light). Rimegepant is in a class of medications called calcitonin gene-related peptide receptor antagonists. It works by blocking the action of a certain natural substance in the body that causes migraine headaches. Rimegepant does not prevent migraine attacks or reduce the number of headaches you have.
Side Effects Of Rimegepant
- Rimegepant may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- nausea
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
- shortness of breath
- trouble breathing
- swelling of the face, eyes, mouth, throat, tongue, or lips
- rash
- hives
- itching
Rimegepant may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
Warnings & Precautions
Before taking rimegepant:
- tell your doctor and pharmacist if you are allergic to rimegepant, any other medications, or any of the ingredients in rimegepant orally disintegrating tablets. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antifungals such as fluconazole (Diflucan), itraconazole (Onmel, Sporanox, Tolsura), ketoconazole, and voriconazole (Vfend); aprepitant (Emend), clarithromycin, ciprofloxacin (Cipro), conivaptan (Vaprisol), crizotinib (Xalkori), cyclosporine (Gengraf, Neoral, Sandimmune), diltiazem (Cardizem, Cartia, Taztia, Tiazac), dronedarone (Multaq), erythromycin (E.E.S., Eryc, Eryped, Ery-tab), fluvoxamine (Luvox); imatinib (Gleevac); medications for human immunodeficiency virus (HIV) such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra, in Viekira), and saquinavir (Invirase), tipranavir (Aptivus); rifampin (Rifadin, Rimactane, in Rifamate, Rifater), and verapamil (Calan, Verelan, in Tarka). Your doctor may need to change the doses of your medications, how often or if you should take rimegepant, or monitor you carefully for side effects. Many other medications may also interact with rimegepant, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
- tell your doctor if you have or have ever had kidney or liver problems.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking rimegepant, call your doctor.
Dosage Of Rimegepant
Rimegepant comes as an orally disintegrating tablet (tablet that dissolves quickly in the mouth) to take by mouth. It is usually taken as a single dose at the first sign of a migraine headache. Do not take more than one dose in a 24-hour period. Your doctor will tell you the maximum number of migraine headaches you should treat with rimegepant tablets in a 30-day period. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take rimegepant exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Do not try to push the orally disintegrating tablet through the foil packaging. Instead, use dry hands to peel back the foil. Immediately take out the tablet and place it on or under your tongue. The tablet will quickly dissolve and can be swallowed with saliva. No water is needed to swallow disintegrating tablets.
Call your doctor if your headaches do not get better or occur more frequently after taking rimegepant.
Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.
Other
Keep all appointments with your doctor.
You should keep a headache diary by writing down when you have headaches and when you take rimegepant.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Source
All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.
