Uses
Rotigotine transdermal patches are used to treat the signs and symptoms of Parkinson’s disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) including shaking of parts of the body, stiffness, slowed movements, and problems with balance. Rotigotine transdermal patches are also used to treat restless legs syndrome (RLS or Ekbom syndrome; a condition that causes discomfort in the legs and a strong urge to move the legs, especially at night and when sitting or lying down).
Rotigotine is in a class of medications called dopamine agonists. It works by acting in place of dopamine, a natural substance produced in the brain that is needed to control movement.
Side Effects Of Rotigotine Transdermal Patch
Rotigotine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- rash, redness, swelling, or itching of the skin that was covered by the patch
- nausea
- vomiting
- constipation
- loss of appetite
- drowsiness
- difficulty falling asleep or staying asleep
- abnormal dreams
- dizziness or feeling that you or the room is moving
- headache
- fainting
- weight gain
- swelling of the hands, feet, ankles, or lower legs
- increased sweating
- dry mouth
- loss of energy
- joint pain
- abnormal vision
- sudden movements of legs or worsening of symptoms of PD or RLS
- rapid or irregular heartbeat
Some side effects of rotigotine transdermal patch can be serious. If you experience any of these symptoms or those listed in the WARNINGS and PRECAUTIONS section, call your doctor immediately:
- difficulty breathing or swallowing
- hives
- rash
- itching
- seeing things or hearing voices that do not exist (hallucinating)
- feeling unusually suspicious of others
- confusion
- aggressive or unfriendly behavior
- having strange thoughts or beliefs that have no basis in reality
- agitation
- frenzied or abnormally excited mood
- People who have Parkinson’s disease may have a greater risk of developing melanoma (a type of skin cancer) than people who do not have Parkinson’s disease. There is not enough information to tell whether medications used to treat Parkinson’s disease such as rotigotine increase the risk of developing skin cancer. You should have regular skin examinations to check for melanoma while you are using rotigotine even if you do not have Parkinson’s disease. Talk to your doctor about the risk of using rotigotine.
Rotigotine transdermal patch may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
Warnings & Precautions
Before using the rotigotine patch:
- tell your doctor and pharmacist if you are allergic to rotigotine, sulfites, or any other medications, or any of the ingredients in rotigotine transdermal patches. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants, medications for anxiety, medications for mental illness, medications for seizures, metoclopramide (Reglan), sedatives, sleeping pills, and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have asthma, high or low blood pressure, mental illness, daytime sleepiness from a sleep disorder or if you have had times that you fell asleep suddenly and without warning during the daytime or heart disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using rotigotine transdermal patch, call your doctor.
- you should know that rotigotine may make you drowsy or may cause you to suddenly fall asleep during your regular daily activities. You might not feel drowsy before you suddenly fall asleep. Do not drive a car or operate machinery at the beginning of your treatment until you know how the medication affects you. If you suddenly fall asleep while you are doing something such as watching television or riding in a car, or if you become very drowsy, call your doctor. Do not drive or operate machinery until you talk to your doctor.
- remember that alcohol can add to the drowsiness caused by this medication. Tell your doctor if you regularly drink alcoholic beverages.
- you should know that rotigotine may cause dizziness, lightheadedness, fainting, or sweating when you get up too quickly from a lying position. This is more common when you first start using rotigotine or as the dose is being increased. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
- you should know that your blood pressure may increase during your treatment with rotigotine transdermal patch. Your doctor will probably monitor your blood pressure during your treatment.
- you should know that transdermal rotigotine can cause burns on your skin if you are having magnetic resonance imaging (MRI; a radiology technique designed to show the images of body structures) or cardioversion (a procedure to normalize the heart rhythm). Tell your doctor that you are using transdermal rotigotine if you are to have either of these procedures.
- you should know that some people who used medications such as transdermal rotigotine developed intense urges or behaviors that were compulsive or unusual for them, such as gambling, increased sexual urges or behaviors, excessive shopping, and binge eating. Call your doctor if you have intense urges to shop, eat, have sex, or gamble, or you are unable to control your behavior. Tell your family members about this risk so that they can call the doctor even if you do not realize that your gambling or any other intense urges or unusual behaviors have become a problem.
Dosage Of Rotigotine Transdermal Patch
- Transdermal rotigotine comes as a patch to apply to the skin. It is usually applied once a day. Apply the rotigotine patch at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use rotigotine exactly as directed.
- Your doctor will probably start you on a low dose of rotigotine and gradually increase your dose, not more often than once a week.
- Rotigotine controls the symptoms of Parkinson’s disease and restless legs syndrome but does not cure them. It may take several weeks before you feel the full benefit of rotigotine. Continue to use rotigotine patches even if you feel well. Do not stop using rotigotine transdermal patches without talking to your doctor. If you suddenly stop using rotigotine transdermal patches, you may experience fever, muscle stiffness, change in consciousness, or other symptoms. Your doctor will probably decrease your dose gradually.
- Apply the patch to an area on the stomach, thigh, hip, flank (side of the body between the ribs and pelvis), shoulder, or upper arm. The area of skin should be clean, dry and healthy. Do not apply the patch to skin that is oily, red, irritated, or injured. Do not use creams, lotions, ointments, oils, or powders on the area of skin where the patch will be placed. Do not apply the patch to skin folds and areas of skin that could be under a waistband or rubbed by tight clothing. If the patch is to be applied to a hairy area, shave the area at least 3 days before applying the patch. Select a different area of skin each day such as changing from the right side to the left side or by moving from the upper body to the lower body. Do not apply the rotigotine transdermal patch to the same area of skin more often than once every 14 days.
- While you are wearing the patch, keep the area away from other sources of heat such as heating pads, electric blankets, and heated waterbeds; or direct sunlight. Do not take a hot bath or use a sauna.
- Be careful to not dislodge the patch during bathing or physical activity. If the edges of the patch lift, use bandage tape to re-secure it to the skin. If the patch falls off, apply a new patch to a different place on your skin for the rest of the day. The following day, remove that patch and apply a new patch at the usual time.
- If the area of skin that was covered by the patch becomes irritated or develops a rash, do not expose this area to direct sunlight until the skin heals. Exposure to this area to the sun could cause changes in your skin color.
- Do not cut or damage a rotigotine patch.
To apply the patch, follow these steps:
- Hold the two sides of the pouch and pull apart.
- Remove patch from the pouch. Apply the patch right away after removing it from the protective pouch.
- Hold the patch with both hands, with the protective liner on top.
- Bend the edges of the patch away from you so that the S-shaped cut in the liner opens.
- Peel off one-half of the protective liner. Do not touch the sticky surface because the medicine could come off on your fingers.
- Apply the sticky half of the rotigotine transdermal patch to a clean area of skin and remove the remaining liner.
- Press the patch firmly with the palm of your hand for 30 seconds. Go around the edges with your fingers to press them onto the skin. Make sure that the patch is flat against the skin (there should be no bumps or folds in the patch).
- After applying the new patch, be sure to remove the patch from the previous day. Use your fingers to peel it off slowly. Fold the patch in half and press firmly to seal it shut. Dispose of it safely, so that it is out of the reach of children and pets.
- If there is any adhesive left on the skin, gently wash the area with warm water and mild soap or gently rub the area with baby or mineral oil to remove it.
- Wash your hands with soap and water. Do not touch your eyes or any objects until you have washed your hands.
Other
Keep all appointments with your doctor.
Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription rotigotine transdermal patch.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Source
All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.
