Triclabendazole is used to treat fascioliasis (an infection, usually in the liver and bile ducts, caused by flatworms [liver flukes]) in adults and children 6 years of age and older.

Triclabendazole is in a class of medications called anthelmintics. It works by killing the flatworms.

Side Effects Of Triclabendazole

Triclabendazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • abdominal pain
  • heavy sweating
  • dizziness
  • nausea
  • vomiting
  • hives
  • itching
  • headache
  • shortness of breath
  • decreased appetite
  • fever
  • diarrhea

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • yellow skin or eyes

Triclabendazole may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Warnings & Precautions

Before taking triclabendazole:

  • tell your doctor and pharmacist if you are allergic to triclabendazole, albendazole (Albenza), mebendazole (Emverm), any other medications, or any of the ingredients in triclabendazole tablets. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention amiodarone (Nexterone, Pacerone), anagrelide (Agrylin), chloroquine, chlorpromazine, cilostazol, ciprofloxacin (Cipro), citalopram (Celexa), clarithromycin, disopyramide (Norpace), dofetilide (Tikosyn), donepezil (Aricept), dronedarone (Multaq), escitalopram (Lexapro), flecainide (Tambocor), fluconazole (Diflucan), haloperidol (Haldol), ibutilide (Corvert), levofloxacin, methadone (Dolophine, Methadose), moxifloxacin (Avelox), ondansetron (Zuplenz, Zofran), pentamidine (Pentam), phenobarbital phenytoin (Dilantin, Phenytek), pimozide (Orap), procainamide, quinidine (in Nuedexta), sotalol (Betapace, Sorine, Sotylize), and thioridazine. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with triclabendazole, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
  • tell your doctor if you have or have ever had a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death), or the symptoms of prolonged QT interval.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.

Triclabendazole Dosage

Triclabendazole comes as a tablet to take by mouth. It is usually taken every twelve hours for 2 doses. Take triclabendazole with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take triclabendazole exactly as directed. Do not take more or less of it than prescribed by your doctor.

If you cannot swallow the tablet whole or divided it in half, you can crush the tablet and mix it with applesauce. Be sure to eat the mixture within 4 hours of preparing.


Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body’s response to triclabendazole.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.


All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.