Patiromer is used to treat hyperkalemia (high levels of potassium in the blood). Patiromer is in a class of medications called potassium removing agents. It works by removing excess potassium from the body. Patiromer is not used for the emergency treatment of life-threatening hyperkalemia because it takes some time to work.

Side Effects Of Patiromer

Patiromer may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • constipation
  • diarrhea
  • gas
  • stomach discomfort
  • nausea

Patiromer may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Warnings & Precautions

Before taking patiromer:

  • tell your doctor and pharmacist if you are allergic to patiromer, any other medications, or any of the ingredients in the patiromer powder. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • if you are taking any other medications by mouth, take them at least 3 hours before or after patiromer.
  • tell your doctor if you have or have ever had difficulty swallowing, gastrointestinal (GI; affecting the stomach or intestines) surgery, constipation, fecal impaction (a dry hard stool stuck in the rectum), bowel obstruction (blockage in your intestine), a problem with your bowels after bowel surgery, or GI disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking patiromer, call your doctor.

Dosage Of Patiromer

Patiromer comes as a powder to mix with water and take by mouth. It is usually taken along with food once a day. Take patiromer at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take patiromer exactly as directed. Do not take more or less of it, or take it more often than prescribed by your doctor.

You will need to mix the medication powder with water right before you take it. Do not take the powder before it is mixed with water. Do not mix the powder with any other liquid or food, except for water. To prepare each dose of your medication, pour 1/3 cup (about 3 ounces [90 mL]) of water into a cup. Add the contents of the packet(s) of patiromer into the cup along with half of the water and stir well. (You may need to use more than one packet of patiromer to make up your full dose.) Add the remaining half of the water to the cup and stir well. The powder will not completely dissolve and the mixture will look cloudy. You may need to add more water to the cup if the mixture is too thick. Drink the mixture right away. If any powder is left in the cup after drinking it, add more water, stir, and drink right away. Repeat as needed until there is no more powder left in the cup. Mix the medication with water only when you are ready to take it; do not prepare the mixture in advance. Be sure to ask your pharmacist or doctor if you have any questions about how to mix or take this medication.

Do not try to warm patiromer by heating it in a microwave, or adding it to heated foods or liquids.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.


It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body’s response to patiromer.


All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.