BONSITY is a prescription medicine that is like a hormone made by the body called parathyroid hormone or PTH.

  • BONSITY may help to form new bone, increase bone mineral density and bone strength.
  • BONSITY can lessen the number of fractures of the spine and other bones in postmenopausal women with osteoporosis.
  • The effect on fractures has not been studied in men.
  • BONSITY is used in both men and postmenopausal women with osteoporosis who are at high risk for having fractures. BONSITY can be used by people who have had a fracture related to osteoporosis, or who have several risk factors for fracture, or who cannot use other osteoporosis treatments.
  • BONSITY is used in both men and women with osteoporosis due to use of glucocorticoid medicines, such as prednisone, for several months, who are at high risk for having broken bones (fractures). These include men and women with either a history of broken bones, who have several risk factors for fracture, or who cannot use other osteoporosis treatments.

It is not known if it is safe and effective in children.

BONSITY should not be used in children and young adults whose bones are still growing.

Side Effects Of Bonsity

  • Decrease in blood pressure when you change positions. Some people feel dizzy, get a fast heartbeat, or feel faint right after the first few doses. This usually happens within 4 hours of taking it and goes away within a few hours. For the first few doses, take your injections of BONSITY in a place where you can sit or lie down right away if you get these symptoms. If your symptoms get worse or do not go away, stop taking it and call your healthcare provider.
  • Increased calcium in your blood. Tell your healthcare provider if you have nausea, vomiting, constipation, low energy, or muscle weakness. These may be signs that there is too much calcium in your blood.

Common side effects of BONSITY include:

  • nausea
  • joint aches
  • pain

Your healthcare provider may take samples of blood and urine during treatment to check your response.

Also, your healthcare provider may ask you to have follow-up tests of bone mineral density.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of BONSITY. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects.

Warnings & Precautions

Before you take BONSITY, tell your healthcare provider if you:

  • have the condition listed in the section “Who should not use BONSITY?”
  • have Paget’s disease or other bone diseases
  • have cancer in your bones
  • have trouble injecting yourself and do not have someone who can help you
  • are a child or young adult whose bones are still growing
  • have or have had kidney stones
  • have had radiation therapy
  • have or have had too much calcium in your blood
  • have any other medical conditions
  • are pregnant or thinking about becoming pregnant. It is not known if BONSITY will harm your unborn baby.
  • are breast-feeding or plan to breast-feed. You should not breast-feed while taking it.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Your healthcare provider needs this information to help keep you from taking BONSITY with other medicines that may harm you.

Especially tell your doctor if you take medicines that contain digoxin (Digoxin∗, Lanoxicaps∗, Lanoxin∗).

Dosage Of Bonsity

  • Inject BONSITY one time each day in your thigh or abdomen (lower stomach area). Talk to a healthcare provider about how to rotate injection sites.
  • Before you try to inject it yourself, a healthcare provider should teach you how to use the BONSITY delivery device to give your injection the right way.
  • Read the detailed User Manual.
  • You can take BONSITY with or without food or drink.
  • The BONSITY delivery device has enough medicine for 28 days. It is set to give a 20-microgram dose of medicine each day. Do not inject all the medicine in the BONSITY delivery device at any one time.
  • Do not transfer the medicine from the BONSITY delivery device to a syringe. This can result in taking the wrong dose of BONSITY. If you do not have pen needles to use with your BONSITY delivery device, talk with your healthcare provider.
  • BONSITY should look clear and colorless. Do not use BONSITY if it has particles in it, or if it is cloudy or colored.
  • Inject BONSITY right away after you take the delivery device out of the refrigerator.
  • After each use, safely remove the needle, recap the delivery device, and put it back in the refrigerator right away.
  • You can take BONSITY at any time of the day. To help you remember to take BONSITY, take it at about the same time each day.
  • If you forget or cannot take it at your usual time, take it as soon as you can on that day. Do not take more than one injection in the same day.
  • If you take more BONSITY than prescribed, call your healthcare provider. If you take too much BONSITY, you may have nausea, vomiting, weakness, or dizziness.
  • Follow your healthcare provider’s instructions about other ways you can help your osteoporosis, such as exercise, diet, and reducing or stopping your use of tobacco and alcohol. If your healthcare provider recommends calcium and vitamin D supplements, you can take them at the same time you take it.


Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use BONSITY for a condition for which it was not prescribed. Do not give BONSITY to other people, even if they have the same condition you have.

This Medication Guide summarizes the most important information about BONSITY. If you would like more information, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information about BONSITY that is written for healthcare professionals.


All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.