BYDUREON is an injectable prescription medicine that may improve blood sugar (glucose) in adults with type 2 diabetes mellitus and should be used along with diet and exercise.
- BYDUREON is not recommended as the first choice of medicine for treating diabetes.
- BYDUREON is not a substitute for insulin and is not for use in people with type 1 diabetes or people with diabetic ketoacidosis.
- BYDUREON is a long-acting form of the medicine in BYETTA (exenatide). BYDUREON and BYETTA should not be used at the same time.
- It is not known if BYDUREON can be used in people who have had pancreatitis.
- It is not known if it is safe and effective for use in children.
Side Effects Of Bydureon
BYDUREON may cause serious side effects, including:
- Possible thyroid tumors, including cancer. Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rats or mice, BYDUREON and medicines that work like BYDUREON caused thyroid tumors, including thyroid cancer. It is not known if it will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people.
- Do not use it if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC), or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2
Warnings & Precautions
Before using BYDUREON, tell your healthcare provider about all of your medical conditions, including if you:
- have or have had problems with your pancreas, kidneys, or liver.
- have severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems with digesting food.
- are pregnant or plan to become pregnant. BYDUREON may harm your unborn baby. Tell your healthcare provider if you become pregnant while using it. Talk to your healthcare provider about the best way to control your blood sugar if you plan to become pregnant or while you are pregnant.
- are breastfeeding or plan to breastfeed. It is not known if BYDUREON passes into your breast milk. You should talk with your healthcare provider about the best way to feed your baby while using it.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. BYDUREON may affect the way some medicines work and some medicines may affect the way it works. Before using BYDUREON, talk to your healthcare provider about low blood sugar and how to manage it. Tell your healthcare provider if you are taking other medicines to
treat diabetes including insulin or sulfonylureas.
Do not use it if:
• you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• you are allergic to exenatide or any of the ingredients in BYDUREON. See the end of this Medication Guide for a complete list of ingredients.
Dosage Of Bydureon
Read the Instructions for Use that comes with BYDUREON. Use BYDUREON exactly as your healthcare provider tells you to. BYDUREON should be injected right away after you prepare your dose. Your healthcare provider should show you how to use BYDUREON before you use it for the first time. It is injected under the skin (subcutaneously) of your stomach (abdomen), thigh, or upper arm. Do not inject BYDUREON into a muscle (intramuscularly) or vein (intravenously). Use 1 time each week on the same day each week at any time of the day.
BYDUREON may be taken with or without food. If you miss a dose, take the missed dose as soon as possible if there are at least 3 days (72 hours) until your next scheduled dose. If there are less than 3 days remaining, skip the missed dose and take your next dose on the regularly scheduled day. Do not take 2 doses within 3 days of each other. You may change the day of the week as long as your last dose was given 3 or more days before.
Do not mix insulin and BYDUREON together in the same injection.
You may give an injection of BYDUREON and insulin in the same body area (such as your stomach area), but not right next to each other. Change (rotate) your injection site with each weekly injection. Do not use the same site for each injection.
Do not share your BYDUREON Pen, prefilled syringe, or needles with another person. You may give another person an infection or get an infection from them. Your dose and other diabetes medicines may need to change because of: change in the level of physical activity or exercise, weight gain or loss, increased stress, illness, change in diet, or because of other medicines you take.
Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use BYDUREON for a condition for which it was not prescribed. Do not give it to other people, even if they have the same symptoms you have. It may harm them. You can ask your pharmacist or healthcare provider for information about BYDUREON that is written for health professionals.
All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.