Cytarabine

Uses Of Cytarabine

Cytarabine is used alone or with other chemotherapy drugs to treat certain types of leukemia (cancer of the white blood cells), including acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), and chronic myelogenous leukemia (CML). Cytarabine is also used alone or with other chemotherapy drugs to treat meningeal leukemia (cancer in the membrane that covers and protects the spinal cord and brain). Cytarabine is in a class of medications called antimetabolites. It works by slowing or stopping the growth of cancer cells in your body.

Side Effects Of Cytarabine

Cytarabine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment:

  • ongoing pain that begins in the stomach area but may spread to the back
  • redness, pain, swelling or burning at the site where the injection was given
  • pale skin
  • fainting
  • dizziness
  • fast or irregular heartbeat
  • rash
  • hives
  • itching
  • difficulty breathing or swallowing
  • chest pain
  • yellowing of the skin or eyes
  • dark-colored urine or decreased urination
  • shortness of breath
  • sudden change or loss of vision
  • seizures
  • confusion
  • numbness, burning or tingling in the hands, arms, feet, or legs

Cytarabine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Warnings & Precautions

Before receiving cytarabine injection:

  • tell your doctor and pharmacist if you are allergic to cytarabine or any of the ingredients in cytarabine injection. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: digoxin (Lanoxin), flucytosine (Ancobon), or gentamicin. Other medications may also interact with cytarabine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
  • tell your doctor if you have or have ever had kidney or liver disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. You should not become pregnant while you are receiving cytarabine injection. If you become pregnant while receiving cytarabine, call your doctor. Cytarabine may harm the fetus.

Dosage

Cytarabine comes as a powder to mixed with liquid to be injected intravenously (into a vein), subcutaneously (under the skin), or intrathecally (into the fluid-filled space of the spinal canal) by a doctor or nurse in a medical facility. Your doctor will tell you how often you will receive cytarabine. The schedule depends on the condition you have and on how your body responds to the medication.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.

Other

Keep all appointments with your doctor and the laboratory.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Source

All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.