Serogroup B Meningococcal Vaccine (MenB)

Uses

Meningococcal disease is a serious illness caused by a type of bacteria called Neisseria meningitidis. It can lead to meningitis (infection of the lining of the brain and spinal cord) and infections of the blood. Meningococcal disease often occurs without warning even among people who are otherwise healthy – but the serogroup B meningococcal vaccine (MenB) can help.

Meningococcal disease can spread from person to person through close contact (coughing or kissing) or lengthy contact, especially among people living in the same household. There are at least 12 types of Neisseria meningitidis, called ”serogroups.” Serogroups A, B, C, W, and Y cause most meningococcal disease. Anyone can get meningococcal disease but certain people are at increased risk, including:

  • Infants younger than one year old
  • Adolescents and young adults 16 through 23 years old
  • People with certain medical conditions that affect the immune system
  • Microbiologists who routinely work with isolates of N. meningitidis
  • People at risk because of an outbreak in their community

Even when it is treated, meningococcal disease kills 10 to 15 infected people out of 100. And of those who survive, about 10 to 20 out of every 100 will suffer disabilities such as hearing loss, brain damage, amputations, nervous system problems, or severe scars from skin grafts. Serogroup B meningococcal (MenB) vaccines can help prevent meningococcal disease caused by serogroup B. Other meningococcal vaccines are recommended to help protect against serogroups A, C, W, and Y.

Side Effects Of Serogroup B Meningococcal Vaccine (MenB)

With any medicine, including vaccines, there is a chance of reactions. These are usually mild and go away on their own within a few days, but serious reactions are also possible.

Mild problems:

  • More than half of the people who get serogroup B meningococcal vaccine have mild problems following vaccination. These reactions can last up to 3 to 7 days, and include:
  • Soreness, redness, or swelling where the shot was given
  • Tiredness or fatigue
  • Headache
  • Muscle or joint pain
  • Fever or chills
  • Nausea or diarrhea

Problems that could happen after any injected vaccine:

  • People sometimes faint after a medical procedure, including vaccination. Sitting or lying down for about 15 minutes can help prevent fainting, and injuries caused by a fall. Tell your doctor if you feel dizzy, or have vision changes or ringing in the ears.
  • Some people get shoulder pain that can be more severe and longer-lasting than the more routine soreness that can follow injections. This happens very rarely.
  • Any medication can cause a severe allergic reaction. Such reactions from a vaccine are very rare, estimated at about 1 in a million doses, and would happen within a few minutes to a few hours after the vaccination.

Warnings & Precautions

Tell the person who is giving you the vaccine:

  • If you have any severe, life-threatening allergies. If you have ever had a life-threatening allergic reaction after a previous dose of serogroup B meningococcal vaccine, or if you have a severe allergy to any part of this vaccine, you should not get the vaccine. Tell your healthcare provider if you have any severe allergies that you know of, including a severe allergy to latex. He or she can tell you about the vaccine’s ingredients.
  • If you are pregnant or breastfeeding. There is not very much information about the potential risks of this vaccine for a pregnant woman or breastfeeding mother. It should be used during pregnancy only if clearly needed.
  • If you have a mild illness, such as a cold, you can probably get the vaccine today. If you are moderately or severely ill, you should probably wait until you recover. Your doctor can advise you.

Dosage Of Serogroup B Meningococcal Vaccine (MenB)

Two serogroup B meningococcal group B vaccines (Bexsero and Trumenba) have been licensed by the Food and Drug Administration (FDA). These vaccines are recommended routinely for people 10 years or older who are at increased risk for serogroup B meningococcal infections, including:

  • People at risk because of a serogroup B meningococcal disease outbreak
  • Anyone whose spleen is damaged or has been removed
  • Anyone with a rare immune system condition called ”persistent complement component deficiency”
  • Anyone taking a drug called eculizumab (also called Soliris®)
  • Microbiologists who routinely work with N. meningitidis isolates
  • These vaccines may also be given to anyone 16 through 23 years old to provide short term protection against most strains of serogroup B meningococcal disease; 16 through 18 years are the preferred ages for vaccination.
  • For best protection, more than 1 dose of a serogroup B meningococcal vaccine is needed. The same vaccine must be used for all doses. Ask your health care provider about the number and timing of doses.

Other

Ask your health care provider. He or she can give you the vaccine package insert or suggest other sources of information.

Call your local or state health department.

Source

All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.