Prasterone Vaginal

Prasterone Vaginal
Prasterone Vaginal


Vaginal prasterone is used to treat changes in and around the vagina due to menopause (“change of life,” the end of monthly menstrual periods) that can cause painful sexual intercourse. Prasterone is in a class of medications called steroids. It works by replacing hormones that are normally produced in the body.

Side Effects Of Prasterone Vaginal

Vaginal prasterone may cause side effects. Tell your doctor if this symptom is severe or does not go away:

It may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

Warnings & Precautions

Before using vaginal prasterone:

  • tell your doctor and pharmacist if you are allergic to prasterone, any other medications, or any of the ingredients in it. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have any vaginal bleeding. Your doctor may tell you not to use vaginal prasterone.
  • tell your doctor if you have or have ever had breast cancer.
  • you should not use prasterone unless you have already undergone menopause and cannot become pregnant. However, tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using prasterone, call your doctor.

Prasterone Vaginal Dosage

Vaginal prasterone comes as an insert to place in the vagina. It is usually used once a day at bedtime. Use vaginal prasterone at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use vaginal prasterone exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Vaginal prasterone comes with a special applicator to use to place the insert into your vagina. Your medication will come with instructions for use. Read these instructions and follow them carefully. Ask your doctor or pharmacist if you have any questions about how to use vaginal prasterone.

Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.


Keep all appointments with your doctor.

Before having a Pap smear (a test to detect cancer of the cervix), tell your doctor or the laboratory personnel that you are using vaginal prasterone.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.


All information has been provided courtesy of MedLinePlus from the National Library of Medicine and from the FDA.